T lymphocytes, so named because they develop in the thymus, are responsible for “cellular” immunity.B lymphocytes participate in the humoral component of the adaptive immune system and secrete antibodies.Monocytes, also part of the innate immune system, are converted to tissue macrophages that engulf foreign substances.They make up 40-70% of all peripheral white blood cells and are part of the innate immune system. Neutrophils form a front-line defense against invading pathogens and respond to infections and injuries.It helps to understand that the population of white blood cells actually contains at least four subtypes, depending on how you count: neutrophils (including eosinophils and basophils), monocytes, B- and T-lymphocytes. Its clinical significance is the triple impact of anemia (decreased tissue oxygen supply), thrombocytopenia (bleeding), and neutropenia (susceptibility to infection).Ĭonfusion arises because the literature sometimes defines pancytopenia as low counts of red blood cells, platelets, and white blood cells. Pancytopenia is a simultaneous deficiency of three blood cell lineages: red blood cells, platelets, and neutrophils.

Icd 10 code for thrombocytopenia